Following Content Provided by USANA, The Cellular Nutrition Company
The discovery of coenzyme Q10 was not a simple accident but rather the result of a long train of tests by numerous researchers into the mechanisms and compounds involved in energy conversion.
Coenzyme Q10 was discovered in 1957 by Dr. Frederick Crane and his team.
There are some vitamin-like nutrients that are essential to our diet. They are necessary for survival, and we do produce a small amount of them on our own. However, the amount we produce may not be the most optimal levels for health. Coenzyme Q10 and Choline both occur naturally in animal products like eggs and meat, and can also be found in supplement form.
Coenzyme Q10, or ubiquinone, is a compound with an essential role in mitochondrial electron transport, making it a fundamental part of cellular energy production. Coenzyme Q10 is also an antioxidant. Its ability to quench free radicals helps maintain the structural integrity and stability of cell membranes (including intracellular membranes). It is also capable of improving oxidation resistance of low-density lipoprotein (LDL) cholesterol. Additional evidence suggests that Coenzyme Q10 uses its antioxidant capabilities to regenerate vitamin E.
CoQ10’s other name, ubiquinone, signifies its ubiquitous (widespread) distribution in the human body. Highest levels of Coenzyme Q10 are found in the heart, liver, kidney, and pancreas. CoQ10 supplementation has therapeutic benefits for several diseases. Some of the best-documented effects involve cases of heart failure, ischemic heart disease, certain muscular dystrophies, hypertension, and periodontal disease.
CoQ10 is synthesized in all cells of the body. It is also absorbed from food. Major sources of dietary CoQ10 include meats, fish, and vegetable oils (particularly soybean, sesame, and rapeseed oils). Vegetables are generally low in CoQ10, with the exception of spinach and broccoli. As aging occurs, the body’s ability to synthesize CoQ10 diminishes significantly. Deficiencies may also result from reduced assimilation from dietary sources.
Coenzyme Q10 supplements are generally considered safe and are best absorbed by the body when taken with foods. The usual maintenance dose is 10-30 mg per day, although higher doses are used therapeutically for the treatment of heart and blood vessel disease.
USANA’s Coquinone 30
CoQuinone contains advanced levels of Coenzyme Q10, a nutrient synthesized and used by every cell in the body due to its essential role in the electron transport chain and ATP production. Coenzyme Q10 has also been shown to support a strong and healthy cardiovascular system, as well as contributing to overall antioxidant protection.
CoQuinone also includes alpha lipoic acid in its highly bioavailable formula.
Coenzyme Q10 Source
The Coenzyme Q10 used in CoQuinone and other USANA products is produced microbiologically in fermentation, then purified.
Ubiquinol or Ubiquinone?
USANA uses solubilized ubiquinone for its CoQuinone products.
There is very little difference in the benefits and bioavailability of ubiquinone and ubiquinol at levels typically provided by dietary supplements. If you read most ubiquinol marketing closely, claims like “ubiquinol is 8 times more absorbable than ubiquinone” often appear. The catch is that this statement is only true when a well-made solubilized form of ubiquinol is compared to a poor form of ubiquinone (either a powder, tablet, or oil gel). In comparison, USANA’s solubilized ubiquinone is also ~8 times more absorbable than powdered and tableted ubiquinone.
Well-formulated ubiquinol and ubiquinone products are not significantly different at dosages normally taken (30-300 mg). It is true to state that at very advanced dosages (several hundred to 3,000 mg), ubiquinol has some advantages – but these dosages are the exception, not the rule. Based on current research and the many papers we have reviewed, the only real difference between ubiquinol and ubiquinone at common dosages is the price and the amount of hype, because the pharmacokinetics of ubiquinol and ubiquinone are virtually identical at these levels.
Following Content Provided by University of Maryland Medical Center
Coenzyme Q10 (CoQ10) is a substance that helps convert food into energy. CoQ10 is found in almost every cell in the body, and it is a powerful antioxidant.
Antioxidants fight damaging particles in the body known as free radicals, which damage cell membranes, tamper with DNA, and even cause cell death. Scientists believe free radicals contribute to the aging process, as well as a number of health problems, including heart disease and cancer. Antioxidants, such as CoQ10, can neutralize free radicals and may reduce or even help prevent some of the damage they cause.
Some studies suggest that coenzyme Q10 supplements, either by themselves or in with other drug therapies, may help prevent or treat the following conditions:
After Heart Attack
Heart failure (HF)
High blood pressure
Heart damage caused by chemotherapy
Gum (Periodontal) disease
Preliminary clinical studies also suggest that CoQ10 may:
Improve immune function in people with HIV or AIDS
Increase sperm motility, improving male fertility
Be used as part of the treatment for Parkinson disease
Improve exercise ability in people with angina
Help prevent migraines
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