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1938: Vitamin B5

The following info on Vitamin B5 Pantothenic Acid is provided by my Nutritional Partner: USANA The Cellular Nutrition Company

Vitamin B5 (Pantothenic Acid) is another water-soluble vitamin that is part of the vitamin B complex group.

It plays an important role in the healthy metabolizing carbohydrates, fats, and proteins.  It also helps support the body’s natural cell renewal processes.

Roger J. Williams and R.W. Truesdail discovered vitamin B5 in 1931, and it was isolated in 1938.

B5 is found throughout all living cells, hence it’s scientific name deriving from the Greek word “pantos”, meaning “everywhere”. 18

Nutritional Bite Link: 18

Pantothenic acid (sometimes referred to as vitamin B5) is a water-soluble nutrient widely synthesized by plants and many bacteria, and essential in the diets of all vertebrate animals, including man. The principal active form of pantothenic acid is coenzyme A (CoA), a more complex molecule synthesized from pantothenic acid, the amino acid cysteine, and adenosine triphosphate (ATP). 95% of this coenzyme is found in mitochondria.

As a component of coenzyme A, pantothenic acid is essential for the production of energy from carbohydrates, fat, and protein. Its pivotal role in energy metabolism involves the formation of acetyl CoA, which in turn combines with oxaloacetic acid to form citrate. This reaction initiates the tricarboxylic acid cycle (Krebs cycle) which ultimately leads to the production of ATP, the cell’s principal energy currency.

Because it is essential for all forms of life, pantothenic acid is widely distributed in nature. The richest food sources include organ meats, yeast, egg yolk, broccoli, and milk.
No cases of oral toxicity of pantothenic acid have ever been reported in humans.

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Basic Description

Pantothenic acid (also known historically as Vitamin B5) is among the most important of the B vitamins for the basic processes of life while also being one of the less likely nutrient deficiencies in the average U.S. diet.

One factor helping to prevent pantothenic acid deficiency is the U.S. diet is its common presence in so many different foods. In fact, the common presence of pantothenic acid in foods is referred to in the naming of this vitamin, since the word pantothen in Greek translates as "on all sides" or "from all "quarters." Among our 100 core WHFoods, 99% contain some measurable amount of pantothenic acid! (Only one of our foods lacks pantothenic acid, and that food is olive oil. While olives themselves contain a small amount of this vitamin, this small amount is lost when the oil is pressed out of the olives since the oil is 100% fat and pantothenic acid is a water-soluble vitamin.)

Without pantothenic acid, you would be unable to use fats, carbohydrates, or proteins as energy sources. You would also be unable to make hormones and your immune system would collapse. These are only some of the important functions that pantothenic acid has.

Role in Health Support
Energy Production
The most studied role of pantothenic acid in health support is its incorporation into a molecule called Coenzyme A (CoA). This molecule is arguably on the short list of the most important chemicals needed to sustain life. In fact, CoA is so important that one recent research group suggested that the origin of life could be traced back to the evolution of this chemical.

CoA occupies a central place in energy metabolism, acting to allow carbohydrates, fats, and proteins to be burned as fuel sources. Given this critical role, it is a very good thing that pantothenic acid is so ubiquitous in foods. We wouldn't exist without it.

Fat Metabolism
In addition to breaking down fats as fuel, pantothenic acid—via the CoA molecule—is necessary for building fats for storage. You'll also need CoA to build cholesterol in the body, which in turn acts as a building block for key hormones that guide metabolic processes. (While many public health organizations warn about risks related to excess presence of cholesterol in the body, a certain amount of cholesterol is critical for health since many types of cells require cholesterol in their membranes and cholesterol is also required for production of certain hormones and vitamin D production.)

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Here is more insight about Vitamin B5 (Pantothenic Acid) from Vitamins in Motion:


Also known as: Pantothenic acid
Important for: Metabolism, healing wounds
Animal Sources: Liver, kidneys, heart, sh, chicken, beef, egg yolk, milk Grain/Fruit/Vegetable Sources: Yeast, whole grain cereals, nuts, legumes, vegetables Other sources: White mushrooms


Vitamin B5 is a water soluble vitamin that is part of the vitamin B complex group. Vitamin B5 plays an important role in metabolizing carbohydrates, fats and proteins. In addition, vitamin B5 is important for healing wounds and repairing tissues and cells.


Vitamin B5 was discovered in 1931 by Roger J. Williams and R.W. Truesdail. It was isolated in 1938. Its scienti c name, pantothenic acid, originates from the Greek word “pantos,” meaning “everywhere,” as it can be found throughout all living cells.


While vitamin B5 de ciency is extremely rare because vitamin B5 exists to some extent in all foods, lack of B5 leads to various health problems, including:
• General fatigue • Insomnia
• Depression
• Irritability

• Stomach pains
• Upper respiratory infections
• Nausea
• Vomiting
• Headaches
• Tingling sensations

(“burning feet” syndrome)


• Alcoholics • People who cannot fully absorb vitamins • Women ( Teenage Girls, opinion of Optimal Cells) on oral contraceptives due to certain diseases

Suggested food sources:





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